Here's where the 49ers sit in the 2025 NFL Draft order after San Francisco's 35-10 blowout loss to the Buffalo Bills on Sunday at Highmark Stadium.

The San Francisco 49ers' losses to the Green Bay Packers and Buffalo Bills mark the worst two-game stretch by a defending conference champion since the 1970 merger.

A picturesque setting of snow was the perfect backdrop for a Buffalo Bills team that has now won its fifth straight AFC East title.

The Chiefs were the first team to clinch an NFL playoff berth, but the Bills can one-up them by sealing the AFC East with a win over the 49ers.

The 2024 NFL Week 13 games end with Sunday Night Football as the Buffalo Bills host the San Francisco 49ers. NFL TV schedule, time and how to watch.

It's the Bills vs the 49ers in Week 13 of the 2024 NFL season. Here's how to watch, including time, channel, TV schedule and streaming info.

A pair of Super Bowl hopefuls from each conference meet up on Sunday, Dec. 1 to close out the NFL schedule for the day with the Buffalo Bills hosting the San Francisco 49ers at Highmark Stadium in Orchard Park, NY.

SportsLine's model has simulated San Francisco vs. Buffalo on Sunday Night Football 10,000 times and revealed its SNF picks and NFL predictions

Buffalo Bills star quarterback Josh Allen pulled off another mind-blowing touchdown that had the football world buzzing. During the third quarter of

Brandon Allen is 2-8 in 10 career starts. One of them was against Josh Allen and the Bills but Brandon Allen wore No. 2 in that game with the Denver Broncos. He completed 10 of 25 passes for 82 yards with an interception and was sacked four times as Buffalo won 20-3 on Nov. 24, 2019.