San Francisco fumbled the ball three times and lost all three. Brock Purdy dropped back to pass 20 times for 86 net yards.

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills ...

The Chiefs were the first team to clinch an NFL playoff berth, but the Bills can one-up them by sealing the AFC East with a ...

Bills quarterback Josh Allen and head coach Sean McDermott let loose after their win over the 49ers. The Bills (10-2) took a ...

Buffalo Bills star Josh Allen had a career night as he became the first quarterback to record a passing, rushing and ...

Allen scored a traditional rushing touchdown early in the fourth quarter, giving him three touchdowns on two plays in the ...

Russell Wilson and the Steelers are on the rise after another key win, as the 49ers continue to tumble. Who else won or lost ...

Fantasy football analyst Matt Harmon delivers his thoughts on the major happenings of Week 13's Sunday action.

After U.S. travelers battled through harsh weekend weather to reach home following the Thanksgiving holiday, forecasters say ...

San Francisco 49ers star running back Christian McCaffrey departed Sunday night's snow game against the Buffalo Bills early ...