Lake-effect snow blanketed swaths of the U.S. as Thanksgiving travelers journeyed home this holiday weekend, with more snow ...

Christian McCaffrey pulled up limping after taking a pitch early in their game against the Bills on Sunday night.

The Bills sacked Purdy twice, Greg Rousseau getting one while the other was called a team sack because Purdy lost a fumble ...

The Bills controlled the game on the ground as the snow played a significant role, with Buffalo finishing the game with 220 ...

Welcome to the Week 13 grades! If you're a Bengals fan, it might be time to give up on the season. For the third straight ...

San Francisco 49ers running back Christian McCaffrey was running wild against the Buffalo Bills on Sunday Night Football.

The 49ers season is still trending down and now they're searching for answers on if they can get back on track.

Quarterback Brock Purdy did not waste any time in getting the ball into the hands of 49ers tight end George Kittle on Sunday.

Josh Allen made history in the Buffalo Bills' dominant win against the San Francisco 49ers to clinch the AFC East.

For the fifth straight season, Buffalo will host a home playoff game after their impressive victory in the snow Sunday night.

Josh Allen and Buffalo are quickly emerging as Super Bowl favorites after delivering another stellar performance on Sunday ...

The weather outside was frightful at Highmark Stadium in Orchard Park, New York on Sunday night, but the way the San ...