Josh Allen and Buffalo are quickly emerging as Super Bowl favorites after delivering another stellar performance on Sunday ...

San Francisco quarterback Brock Purdy, after missing one game because of an ailing right shoulder, will start for the 49ers ...

If you didn't know the San Francisco 49ers were Super Bowl contenders last season, you might not believe it now. The 5–6 team ...

The Bills are coming off a bye week and riding a six-game winning streak behind MVP favorite Josh Allen, most recently ...

The San Francisco 49ers' losses to the Green Bay Packers and Buffalo Bills mark the worst two-game stretch by a defending ...

The 49ers just lost 35-10 to the Buffalo Bills. Now the 49ers are 5-7 and all alone in last place in the NFL West. Here are ...

ORCHARD PARK, N.Y. (WROC) — In wintry conditions at Highmark Stadium, the Bills took down the 49ers 35-10 to win their fifth ...

The San Francisco 49ers suffered another crushing defeat Sunday night, falling 35-10 to the Buffalo Bills. The loss marked ...

The temperature in the 49ers' loss to the Bills has something in common with their playoff chances -- it dropped rapidly.

Josh Allen became the first quarterback since 1970 to score a rushing touchdown, pass for a touchdown and have a scoring ...

One week after a 38-10 road loss to the Green Bay Packers that stood out as one of their ugliest defeats in years, the San ...

Buffalo was a perfect 4-for-4 in the red zone. A big factor in the Bills' success was their run game. RB James Cook had 14 ...