Guard Ben Bartch and defensive tackle Evan Anderson got their first-ever starts for the 49ers and both played well in snowy ...

Following a resounding 35-10 victory over the San Francisco 49ers in snow-covered conditions, the Bills turn their attention ...

An 8-year-old cancer survivor's first NFL game turned sour when a Bills fan allegedly pushed her down the stairs at Highmark ...

AP photographers captured some of the greatest moments from around the sports world last week, including action shots, ...

The Bills (10-2) ended up winning in a rout in a 35-10 final over the 49ers (5-7). That was just the start of it. On a ...

The Great Lakes experienced a surge of activity as arctic air passed over record-warm waters, generating prolific snowfall.

Josh Allen’s memorable week began with singer and actress Hailey Steinfeld accepting his proposal for marriage and ended with ...

Now that it's December, the weather can be a much bigger fantasy football factor, especially on defense and special teams.

In Sunday's 35-10 win over the San Francisco 49ers, The Buffalo Bills used Alec Anderson as a third tackle on 17 plays, and ...

Isaac Guerendo and Will Levis are among UPI senior sports writer Alex Butler's top fantasy football waiver wire priorities ...

Donations have flooded in for the cancer survivor who was allegedly pushed down the stairs at Sunday's Bills game, with her ...

RB Christian McCaffrey suffers potentially season-ending knee injury in loss to Bills, adding to team's struggles.