SAN FRANCISCO - The San Francisco Police Department is investigating two separate homicides that occurred in the city Friday. The first homicide occurred around 6:25 a.m. on Mission and Sycamore ...

The Bills controlled the game on the ground as the snow played a significant role, with Buffalo finishing the game with 220 ...

Facing their seventh loss of the season, 49ers HC Kyle Shanahan gave an update on RB Christian McCaffrey who left the game ...

Lake-effect snow blanketed swaths of the U.S. as Thanksgiving travelers journeyed home this holiday weekend, with more snow ...

The San Francisco 49ers can't catch a break.Running back Christian McCaffrey left Sunday's 35-10 loss to the Buffalo Bills in ...

The Buffalo Bills host the San Francisco 49ers on Sunday Night Football in a week 13 clash.The Bills (9-2) are coming off six-straight wins while the Niners (5-6) have lost back-to-back games coming ...

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills clinched their fifth straight AFC East title with a 35-10 victory over the San ...

San Francisco 49ers running back Christian McCaffrey's season might be over after he suffered a PCL injury on "Sunday Night ...

Officials in upstate New York counties have declared a state of emergency as they prepare for a major snowstorm that has ...

The Buffalo Bills dominated the San Francisco 49ers on Sunday night, winning 35-10 in Highmark Stadium in Orchard Park, N.Y.

Snow flew like confetti in celebration from the packed stands as the Bills became the first team since 2009 to clinch a ...