The 49ers keep losing key players to injuries. The latest one who could miss time is rookie right guard Dominick Puni. He ...

San Francisco 49ers head coach Kyle Shanahan spoke with reporters via a conference call on Monday, providing several injury ...

The San Francisco 49ers will hold three full practices this week as they prepare for their Week 13 matchup against the ...

The 49ers have a 17% chance of making the playoffs and have one of the toughest remaining schedules -- all while ...

Brian Renick and Al Sacco look for words to describe the current 49ers season, the abysmal effort on defense, the lack of ...

Star receiver George Kittle and the San Francisco 49ers face the Buffalo Bills on Sunday at 8:20 p.m. ET at Highmark Stadium.

On Monday, head coach Kyle Shanahan announced that the San Francisco 49ers would let Jon Feliciano's practice window expire, ...

The 49ers' PFF grades show there is plenty of blame to go around in San Francisco's embarrassing 38-10 loss to the Green Bay ...

The 49ers gave up 169 yards and 3 touchdowns on the ground during their 38-10 loss to the Packers. On Monday, Kyle Shanahan ...

San Francisco 49ers wide receiver Deebo Samuel has been a shadow of his usual dynamic self this season. With just 511 ...

Brandon Allen's first start with the 49ers didn't go so well. He made some nice throws, but he fumbled twice, threw an ...

San Francisco 49ers head coach Kyle Shanahan spoke with reporters via a conference call on Monday, providing several injury ...