“This gene-to-molecule research is crucial for discovery in Alzheimer’s disease. It offers fresh perspectives on how genetic risk factors, such as APOE, influence metabolism and perhaps disease ...

Brain age gap (BAG) is a useful metric because it predicts one’s age-adjusted vulnerability to a range of neurological disorders, such as AD, dementia, and stroke. Although brain age may indeed ...

The hotspot at chr3q28 sits between the GMNC and osteocrin (OSTN) genes. They are involved in DNA replication and dendritic ...

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Strapped with an extra APP, people with Down’s syndrome are all but destined to develop Alzheimer’s dementia if they live ...

Application budgets are limited to $400,000 direct costs per year. The maximum project period is 3 years.

Application budgets are capped at $1 million in direct costs per year. The maximum project period is 5 years.

The combined budget for direct costs for the two-year project period may not exceed $275,000. No more than $200,000 may be requested in any single year. June 02, 2025 (Letter of Intent due May 1, 2025 ...

Tapering. Spaghetti plots show that CSF NFL (right) rises more quickly in people with ADAD mutations (red) than in noncarriers (gray) and that this accelerates as disease progresses. In plasma (left), ...

“The astrocyte response to AD neuropathology is complex and nonlinear, both along spatial and temporal axes,” Das told Alzforum. She hopes the dataset, which is freely available online, will be a ...